Body composition and spontaneous growth hormone secretion in normal short stature children
| Autor: | J E Abdenur, Fima Lifshitz, C V Solans, M M Smith, C Carman, M Pugliese |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Aging Adolescent Endocrinology Diabetes and Metabolism Clinical Biochemistry Physical examination Dwarfism Body adiposity index Biochemistry Short stature Body Mass Index Endocrinology Internal medicine medicine Humans Child Sex Characteristics medicine.diagnostic_test Anthropometry business.industry Biochemistry (medical) medicine.disease Obesity Growth hormone secretion Body Height El Niño Adipose Tissue Growth Hormone Body Composition Female medicine.symptom business Body mass index |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 78(2) |
| ISSN: | 0021-972X |
| Popis: | This study was designed to compare the relationship of measured and estimated indices of adiposity with the spontaneous GH secretion (SGHS) in 37 normal short stature children. Fifteen of the 37 patients (10 males and 5 females) were pubertal, and 22 (17 males and 5 females) were prepubertal. All patients underwent a review of their medical history, a physical exam, laboratory tests, and a nutritional assessment that included anthropometry and evaluation of body composition by bioelectric impedance. The percentage of body fat and body fat mass index were used as measured indices of adiposity. The weight for height ratio, body mass index, and body mass index z-scores were calculated and used as estimated indices of adiposity. Our results showed that SGHS is greatly influenced by variations in adiposity in normal short stature children, and measured indices of adiposity demonstrated the strongest negative correlation with SGHS. Gender differences were apparent in the degree of adiposity that modified SGHS, and it appears that adiposity altered the amplitude of GH pulses in pubertal patients and the number of pulses in prepubertal children. These results suggest that interpretation of SGHS must take into account body composition and gender in addition to pubertal status. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|