Prevalence and concordance of HPV, HIV, and HSV-2 in heterosexual couples in Kigali, Rwanda
| Autor: | Ammiel Gasarabwe, Rosetta Busasa, Joseph Vyankandondera, Janneke van de Wijgert, Nathalie Dhont, Tania Crucitti, Nienke J. Veldhuijzen |
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| Přispěvatelé: | Global Health, Infectious diseases |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Epidemiology Herpesvirus 2 Human Human immunodeficiency virus (HIV) Herpes simplex virus type 2 medicine.disease_cause Cohort Studies Interquartile range HIV Seropositivity Prevalence Medicine Cancer Obstetrics Risk behavior virus diseases Men HSV-2 Infectious Diseases Sexual Partners Female Microbiology (medical) Adult Discordance medicine.medical_specialty Genotyping Concordance Cervix neoplasms Couples Dermatology Viral diseases Humans Women Africa Central Cervix neoplasm Heterosexuality Sampling interval Herpes Genitalis Disease transmission sexual business.industry Papillomavirus Infections Public Health Environmental and Occupational Health Heterosexual Social aspects Rwanda HIV Confidence interval Cross-Sectional Studies business Serostatus |
| Zdroj: | Sexually transmitted diseases, 39(2), 128-135. Lippincott Williams and Wilkins |
| ISSN: | 0148-5717 |
| Popis: | BACKGROUND: : In the absence of prospectively collected transmission data, the transmission potential of a sexually transmissible infection (STI) can be estimated by its proxy of concordance in sexual partners. Here we report concordance data of 3 viral STIs: human papillomavirus (HPV), HIV, and herpes simplex virus type 2 (HSV-2) among heterosexual couples in Kigali, Rwanda. METHODS: : Cervical and penile HPV typing was performed among 166 community-sampled fertile couples in Kigali, Rwanda (median sampling interval 10 days (interquartile range: 5-36). HIV and HSV-2 serostatus, curable STIs, and sociobehavioral and clinical characteristics were also assessed. RESULTS: : Concordance rates for all 3 viral STIs were higher than expected by chance alone. Positive concordance among couples was 25% for HSV-2, 15.7% for any HPV, 8.4% for high-risk (HR)-HPV, and 6% for HIV. HR-HPV prevalence among women and men was 19.9% and 26.5%, respectively. Partner's HIV status was more strongly associated with HR-HPV detection in men (OR: 8.5; confidence interval: 2.9-24.6) than in women (OR: 1.9; confidence interval 0.5-6.7). CONCLUSION: : More than half of the couples were discordant for HIV, HPV, and/or HSV-2, indicating that prevention strategies directed to infected cases are important to protect their uninfected sexual partners. |
| Databáze: | OpenAIRE |
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