Automation in the life science research laboratory
| Autor: | Jamie A. Davies, Ian Holland |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Histology Exploit lcsh:Biotechnology Biomedical Engineering Bioengineering 02 engineering and technology Environmental design Review innovation inhibition 03 medical and health sciences lcsh:TP248.13-248.65 reproducibility laboratory automation Protocol (science) research efficiency business.industry Bioengineering and Biotechnology Modular design 021001 nanoscience & nanotechnology Automation environmental design Engineering management 030104 developmental biology Obsolescence Laboratory automation life science research automation design 0210 nano-technology business Host (network) Biotechnology |
| Zdroj: | Holland, I & Davies, J A 2020, ' Automation in the life science research laboratory ', Frontiers in Bioengineering and Biotechnology . https://doi.org/10.3389/fbioe.2020.571777 Frontiers in Bioengineering and Biotechnology Frontiers in Bioengineering and Biotechnology, Vol 8 (2020) |
| DOI: | 10.3389/fbioe.2020.571777 |
| Popis: | Protocols in the academic life science laboratory are heavily reliant on the manual manipulation of tools, reagents and instruments by a host of research staff and students. In contrast to industrial and clinical laboratory environments, the usage of automation to augment or replace manual tasks is limited. Causes of this 'automation gap' are unique to academic research, with rigid short-term funding structures, high levels of protocol variability and a benevolent culture of investment in people over equipment. Automation, however, can bestow multiple benefits through improvements in reproducibility, researcher efficiency, clinical translation, and safety. Less immediately obvious are the accompanying limitations, including obsolescence and an inhibitory effect on the freedom to innovate. Growing the range of automation options suitable for research laboratories will require more flexible, modular and cheaper designs. Academic and commercial developers of automation will increasingly need to design with an environmental awareness and an understanding that large high-tech robotic solutions may not be appropriate for laboratories with constrained financial and spatial resources. To fully exploit the potential of laboratory automation, future generations of scientists will require both engineering and biology skills. Automation in the research laboratory is likely to be an increasingly critical component of future research programs and will continue the trend of combining engineering and science expertise together to answer novel research questions. |
| Databáze: | OpenAIRE |
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