The Role of Singlet Oxygen in Photoreactivity and Phototoxicity of Curcumin

Autor: Agnieszka Wolnicka‐Glubisz, Magdalena Olchawa, Mariusz Duda, Pawel Pabisz, Anna Wisniewska‐Becker
Rok vydání: 2022
Předmět:
Zdroj: Photochemistry and Photobiology. 99:57-67
ISSN: 1751-1097
0031-8655
DOI: 10.1111/php.13666
Popis: Curcumin is a plant-derived yellow-orange compound widely used as a spice, dye and food additive. It is also believed to have therapeutic effects against different disorders. On the other hand, there are data showing its phototoxicity against bacteria, fungi and various mammalian cells. Since the mechanism of its phototoxic action is not fully understood, we investigated here the phototoxic potential of curcumin in liposomal model membranes and in HaCaT cells. First, detection of singlet oxygen (
Databáze: OpenAIRE