Molecular mechanisms in palatal rugae development
| Autor: | Supaluk Trakanant, Maiko Kawasaki, Isao Saito, Katsushige Kawasaki, Maeda Takeyasu, Akane Yamada, Atsushi Ohazama, Jun Nihara, Fumiya Meguro |
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| Rok vydání: | 2020 |
| Předmět: |
Palate
Hard 0301 basic medicine Mouth Mucosa Medicine (miscellaneous) 030206 dentistry Biology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Gene Expression Regulation Evolutionary biology Animals Humans Palatal rugae General Dentistry |
| Zdroj: | Journal of Oral Biosciences. 62:30-35 |
| ISSN: | 1349-0079 |
| Popis: | Background Periodic patterning of iterative structures is diverse across the animal kingdom. Clarifying the molecular mechanisms involved in the formation of these structures helps to elucidate the genetic commonality of developmental processes, as organs with these structures are believed to share the same molecular mechanisms and fundamental processes. Palatal rugae are periodic corrugated structures on the hard palate and are conserved in all mammals. Although the numbers and patterns of the palatal rugae are species specific, they are consistent in each mammalian species, except humans. Highlight Palatal rugae development is thus under strict genetic control in most mammals and is an excellent model to investigate the genetic commonality of developmental processes to form periodic patterning. Conclusion This review highlights the current understanding of the molecular mechanisms of palatal rugae development. |
| Databáze: | OpenAIRE |
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