Percutaneous ultrasound guided radiofrequency and microwave ablation in the treatment of hepatic metastases. A monocentric initial experience
| Autor: | Claudia Hagiu, Rares Craciun, Daniel Corneliu Leucuta, Zeno Sparchez, Adrian Bartos, Mihaela Sparchez, Tudor Mocan, Nadim All Hajjar, Mocan L, Daniela Matei |
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| Rok vydání: | 2019 |
| Předmět: |
Ablation Techniques
Male medicine.medical_specialty Percutaneous Acoustics and Ultrasonics Radiofrequency ablation medicine.medical_treatment 030218 nuclear medicine & medical imaging law.invention Cohort Studies 03 medical and health sciences 0302 clinical medicine law medicine Humans Radiology Nuclear Medicine and imaging Microwaves Ultrasonography Interventional Retrospective Studies Univariate analysis Radiological and Ultrasound Technology business.industry Liver Neoplasms Microwave ablation Ultrasound Retrospective cohort study Middle Aged Ablation Treatment Outcome Liver Tumor progression 030220 oncology & carcinogenesis Catheter Ablation Female Radiology business |
| Zdroj: | Medical Ultrasonography. 21:217 |
| ISSN: | 2066-8643 1844-4172 |
| DOI: | 10.11152/mu-1957 |
| Popis: | Aim: Percutaneous radiofrequency (RFA) and microwave ablation (MWA) are currently the best treatment options forpatients with liver metastases (LM) who cannot undergo a liver resection procedure. Presently, few studies have evaluated theefficacy of tumor ablation in beginner’s hands but none at all in hepatic metastasis. Our aim was to report the initial experiencewith ultrasound as a tool to guide tumor ablation in a low volume center with no experience in tumor ablation.Material and methods: We conducted a retrospective cohort study, on a series of 61 patients who had undergone percutaneous US-guided ablations for 82 LM between 2010 and 2015. Long term outcome predictors were assessed using univariate and multivariate analysis.Results: Complete ablation was achieved in 86.9% of cases (53/61). All MWA sessions (20/20) attained ablation margins >5mm, compared to 79% (49/62) for RFA sessions (p=0.031). Ablation time was significantly shorter for MWA, with a median duration of 10 minutes (range: 6-12) vs. 14 minutes (range: 10-19.5, p=0.003). There was no statistically significant difference in local tumor progression (LTP)-free survival rates between MWA and RFA (p=0.154). On univariate analysis, significant predictors for local recurrence were multiple metastases (p=0.013) and ablation margins |
| Databáze: | OpenAIRE |
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