Conventional Predictors of Survival Poorly Predict and Significantly Underpredict Survival after H-graft Portacaval Shunts

Autor: Desiree Villadolid, Whalen Clark, Emmanuel E. Zervos, Alexander S. Rosemurgy, Donald Thometz, Sarah M. Cowgill, Elizabeth Carey, Daphne Pinkas
Rok vydání: 2007
Předmět:
Zdroj: Journal of Gastrointestinal Surgery. 11:89-94
ISSN: 1873-4626
1091-255X
DOI: 10.1007/s11605-006-0041-7
Popis: This study was undertaken to evaluate the ability to predict survival after 8 mm prosthetic H-graft portacaval shunts (HGPCS).Since 1988, 170 patients have been prospectively followed after HGPCS. Using preshunt data, predictors of survival after shunting [MELD Score, Emory Score, Child Pugh Score, Discriminant Function (DF), and Child Class] were determined and related to actual survival.Child Class was: (a) 10%, (b) 28%, and (c) 62%. Actual 5- and 10-year survival by Child Class was: (a) 67% and 33%, (b) 49% and 16%, (c) 29% and 7%. Survival correlated with all predictors of survival (p0.01 for each). Actual survival was better than predicted by MELD (p0.001). By Multiple Variable Regression Analysis--Computed Model, explained variation in survival was greatest for Child Class (18%), followed by MELD (14%), with DF, Emory Score, and Child Pugh Score not significantly contributing.After HGPCS, actual survival is better than predicted by MELD. Child Class explains only a minor variation in survival, although it better explains survival than MELD, Emory Score, Child Pugh Score, or DF. Conventional predictors of survival poorly and underpredict survival after HGPCS and should be used with caution.
Databáze: OpenAIRE
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