In-vitro antibacterial activity of the seed extract of three-member Artocarpus towards Methicillin-Resistant Staphylococcus aureus (MRSA)
| Autor: | Arifani Rahma Putri, Bagus Dwi Yulianto, Hafizha Dara Haqi, Inas Hasna Azizah, Zhafira Dias Radipasari, Nita Ayu Dwi Astuti, Muhammad Evy Prastiyanto, Aulia Bella Agmala |
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| Rok vydání: | 2020 |
| Předmět: |
lcsh:R5-920
food.ingredient Minimum bactericidal concentration biology Traditional medicine methicillin resistant staphylococcus aureus minimum inhibitory concentration bacterial infections and mycoses medicine.disease_cause biology.organism_classification Methicillin-resistant Staphylococcus aureus artocarpus minimum bactericidal concentration Artocarpus Minimum inhibitory concentration food antibacterial activity Staphylococcus aureus zones of inhibition medicine Agar Agar diffusion test lcsh:Medicine (General) Antibacterial activity |
| Zdroj: | Jurnal Teknologi Laboratorium, Vol 9, Iss 2, Pp 128-135 (2020) |
| ISSN: | 2580-0191 2338-5634 |
| DOI: | 10.29238/teknolabjournal.v9i2.237 |
| Popis: | Methicillin-Resistant Staphylococcus aureus (MRSA) infections have created a critical need for the development of natural antibacterials from a biological source. This research aimed to investigate the antibacterial activity of the seed extract of three-member Artocarpus (Artocarpus heterophyllus, A. champeden, and A. camansi) against MRSA which are the most prevalent causes of infections in patients. Crude seed extracts of three-member Artocarpus were evaluated for their antibacterial activity against MRSA. The antibacterial activity against MRSA of the three extracts was assayed in vitro by the agar well diffusion assay and agar microdilution method and minimum bactericidal concentration. The antibacterial activity, calculated as a zone of inhibition and MIC, MBC values. The Crude seed extracts of three-member Artocarpus showed antibacterial activity against the MRSA in the agar well diffusion assay (1.5-9 mm inhibition diameter). The MIC value of extract showed at 15.62 mg/mL and the MBC value of seed extract of A. heterophyllus at 62.5 mg/mL, A. champeden at 31.25 mg/mL, A. camansi at 250 mg/mL. All seed extracts have the potential to be developed as antibacterial agents, particularly against MRSA strain. Studies on the antibacterial activity against MRSA can provide new information about the benefits seed of members of Artocarpus as a source of natural antibacterial. |
| Databáze: | OpenAIRE |
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