SCI1, the first member of the tissue-specific inhibitors of CDK (TIC) class, is probably connected to the auxin signaling pathway
| Autor: | Gustavo H. Goldman, Henrique C. DePaoli, Maria-Helena S Goldman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Genetics
Cell division Indoleacetic Acids Cell growth Arabidopsis Proteins Short Communication fungi Intracellular Signaling Peptides and Proteins food and beverages Plant Science Cell cycle Biology biology.organism_classification Phenotype Cyclin-Dependent Kinases Cell biology Cyclin-dependent kinase Arabidopsis Transcriptional regulation biology.protein TRANSDUÇÃO DE SINAL CELULAR Gene Protein Kinase Inhibitors Signal Transduction |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| Popis: | The recent finding of a tissue-specific cell cycle regulator (SCI1) that inhibits cell proliferation/differentiation in the upper pistil points to an unanticipated way of controlling plant morphogenesis. The similarity between the SCI1 RNAi-silenced plants and some auxin-related phenotypes suggested that SCI1 could be involved in the auxin signaling pathway. To address this hypothesis, we analyzed the expression of three auxin-related genes in transgenic plants in which SCI1 was silenced and overexpressed. The results showed that the expression levels of the auxin-related genes largely correlated with the SCI1 expression level. Additionally, we analyzed the Arabidopsis SCI1 upstream regulatory region and found putative cis-acting elements also present in the AtCYCB1;1 AtYUC1, AtYUC2 and AtYUC4 URRs, suggesting a cell cycle- and auxin-related transcriptional regulation. Based on our previous and the current studies, we propose SCI1 as a signal transducer engaging auxin signaling and cell division/differentiation. |
| Databáze: | OpenAIRE |
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