Examination of androgenetic alopecia with serum biomarkers
| Autor: | Ahmet Rifat Balik, Zeynep Büşra Balik, Aysun Bay Karabulut, Akın Aktaş, Ercan Karabulut, Salim Neselioglu |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Inflammation Dermatology medicine.disease_cause Nitric oxide 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Fibrosis Internal medicine medicine Humans chemistry.chemical_classification business.industry Alopecia medicine.disease Hair follicle Oxidative Stress Endocrinology medicine.anatomical_structure Hair loss chemistry 030220 oncology & carcinogenesis Thiol Androgens medicine.symptom Thioredoxin business Hair Follicle Oxidative stress Biomarkers |
| Zdroj: | Journal of cosmetic dermatologyREFERENCES. 20(6) |
| ISSN: | 1473-2165 |
| Popis: | BACKGROUND Androgenetic alopecia (AGA) is the most common type of hair loss and affects approximately 50% of the male population. AIMS In the present study, to investigate microinflammation, perifollicular fibrosis, and oxidative stress in AGA cases, some serum biomarker levels were measured and evaluated. PATIENTS/METHODS Serum samples were drawn from patients (n = 58) and control (n = 30) groups referring to Ataturk Training and Investigation Hospital Dermatology Outpatient clinic. In serum samples, NF-κB, TNF-α, TGF-β1, thioredoxin, nitric oxide, TOS, TAS, and thiol disulfide homeostasis (native thiol, total thiol, disulfide) were measured and evaluated. RESULTS In patients with AGA, NF-κB (P = .005), TNF-α (P = .008), TGF-β1 (P = .028), thioredoxin (P = .004), nitric oxide (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|