Complete resolution of extensive thrombosis of atheromatous non-aneurysmal descending aorta and pulmonary embolism with warfarin therapy

Autor: Vishaka Kerner, Steven Kum, Shrikant D Pande, Farah Safdar Husain
Rok vydání: 2018
Předmět:
Male
medicine.medical_specialty
Simvastatin
Aortography
medicine.medical_treatment
warfarin therapy
Aortic Diseases
Embolectomy
Aorta
Thoracic

030204 cardiovascular system & hematology
vascular surgery
03 medical and health sciences
0302 clinical medicine
medicine.artery
Internal medicine
medicine
Thoracic aorta
Humans
Carotid Stenosis
030212 general & internal medicine
cardiovascular diseases
Stroke
Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
medicine.diagnostic_test
business.industry
Heparin
Warfarin
Anticoagulants
Brain
Infarction
Middle Cerebral Artery

General Medicine
Middle Aged
medicine.disease
Thrombosis
stroke
Plaque
Atherosclerotic

Pulmonary embolism
Descending aorta
Cardiology
Drug Therapy
Combination

Hydroxymethylglutaryl-CoA Reductase Inhibitors
business
Pulmonary Embolism
medicine.drug
Zdroj: BMJ Case Reports
ISSN: 1757-790X
Popis: A 54-year-old man underwent decompressive craniectomy following a stroke. He further developed right lower limb ischaemia, and CT aortography revealed extensive aortic atherosclerotic disease. Urgent embolectomy prevented him from having a major amputation. He subsequently developed pulmonary embolism. This was initially treated with heparin followed by warfarin apart from antiplatelets and statin. A follow-up aortography at 3 months interval showed near complete resolution of atheromatous disease of the aorta. This report raises the possibility that apart from antiplatelets and lipid-lowering agents, anticoagulation may be responsible for resolution of such an extensive atheromatous disease and whether this can be considered as part of regular treatment.
Databáze: OpenAIRE