Procedural and late outcomes following MULTI-LINK DUET coronary stent deployment
| Autor: | Mark Midei, Thomas M. Broderick, Stan Fink, Richard Schlofmitz, Dean J. Kereiakes, James B. Hermiller, Naomi Nishimura, Frank B. Hu, Charles O'Shaughnessy, Steven J. Yakubov, Alexandra J. Lansky, Marina Sievers, Jeffrey W. Moses, Marye Ellen Valentine |
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| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Coronary Disease Prosthesis Design law.invention Randomized controlled trial Restenosis law Cause of Death Angioplasty Internal medicine Coronary stent medicine Clinical endpoint Humans Prospective Studies Myocardial infarction Angioplasty Balloon Coronary Aged business.industry Stent Middle Aged medicine.disease Equipment Failure Analysis Radiography Survival Rate Stenosis Treatment Outcome Cardiology Female Stents Radiology Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The American Journal of Cardiology. 84:1385-1390 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/s0002-9149(99)00581-0 |
| Popis: | The MULTI-LINK DUET is the next generation MULTI-LINK stent with modified strut geometry. Safety and efficacy of the MULTI-LINK DUET were evaluated in a prospective multicenter registry and were compared with prior MULTI-LINK stent experience from the ASCENT randomized trial. A total of 270 patients received 302 MULTI-LINK DUET stents and were evaluated using a composite primary end point of major cardiac events (death, Q-wave and non-Q-wave myocardial infarction, and requirement for coronary revascularization) attributable to the target stenosis cumulative to 30 days following enrollment. Quantitative coronary angiography was performed at a mean follow-up of 6 +/- 2 (+/-SD) months. No difference in primary end point or in angiographic restenosis to 6 months was observed between MULTI-LINK DUET and MULTI-LINK experiences. The MULTI-LINK DUET demonstrated improved device and procedural success, less postprocedural in-stent stenosis, larger postprocedural minimal lumen diameter, and fewer postprocedural marginal dissections compared with the MULTI-LINK stent. Multivariate regression modeling identified stent length, diabetes mellitus, poststent minimal lumen diameter, lesion eccentricity, and current smoking as independent predictors of in-stent restenosis. Thus, the MULTI-LINK DUET Registry demonstrates enhanced procedural performance with clinical and angiographic outcomes similar to those previously observed for the MULTI-LINK stent in the ASCENT randomized trial. |
| Databáze: | OpenAIRE |
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