Increased risk of gastric cancer in workers with occupational dust exposure

Autor: Jung-Wan Koo, Hyoung-Ryoul Kim, Inah Kim, Jun-Pyo Myong, Mo-Yeol Kang, Jiyoun Jung
Rok vydání: 2021
Předmět:
Zdroj: The Korean Journal of Internal Medicine, Vol 36, Iss Suppl 1, Pp S18-S26 (2021)
The Korean Journal of Internal Medicine
ISSN: 2005-6648
1226-3303
DOI: 10.3904/kjim.2019.421
Popis: Background/Aims: Workers who are exposed to dust in the workplace tend to show a higher incidence of gastric cancer. Nevertheless, scientific evidence to sup port an association between dust exposure and the risk of gastric cancer is inade quate. This study aimed to investigate whether or not occupational dust exposure influences the risk of gastric cancer. Methods: We collected the electronic data from the Pneumoconiosis Health Ex amination (PHE) program, provided by the Ministry of Employment and Labor and the Korea Workers’ Compensation and Welfare Service from 2002 to 2017. The PHE database was linked to the National Health Insurances databases. The age-standardized incidence ratio (SIR) and 95% confidence intervals (CIs) of the risk of gastric cancers were evaluated in workers with occupational dust exposure, and the results were compared to those in the general population. Results: From 2004 to 2015, 1,543 cases of gastric cancer were observed in the male participants, as compared with 1,174 of expected cases, which yielded an SIR of 1.314 (95% CI, 1.249 to 1.380). Under dust exposure, the risk of gastric cancer was increased 23.9% in the male participants (95% CI, 19.9 to 27.5), and the degree of impairment of lung function was inversely related to the risk of gastric cancer. Conclusions: Workers with occupational dust exposure were at higher risk of de veloping gastric cancer than the general population. Thus, future efforts for the prevention of gastric cancer are necessary for dust exposed workers.
Databáze: OpenAIRE