Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi
| Autor: | Eliza Lamer-Zarawska, Dorota Wozniak, Adam Matkowski |
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| Rok vydání: | 2004 |
| Předmět: |
DPPH
Stereochemistry Flavones Plant Roots Antioxidants chemistry.chemical_compound Wogonin Glucosides Picrates chemistry.chemical_classification Flavonoids biology Traditional medicine Mutagenicity Tests Plant Extracts Biphenyl Compounds Antimutagenic Agents Free Radical Scavengers biology.organism_classification Baicalein Biphenyl compound Hydrazines chemistry Flavanones Scutellaria baicalensis Antimutagen Baicalin Food Science |
| Zdroj: | Die Nahrung. 48(1) |
| ISSN: | 0027-769X |
| Popis: | The four flavonoids baicalin, baicalein, wogonoside, and wogonin have been isolated from Scutellaria baicalensis (Lamiaceae) root extract as main bioactive components. We evaluated their antimutagenic activity as potential chemopreventive natural substances using the Ames test. Free radical scavenging properties have also been measured with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Both crude extract and isolated flavone glycosides and aglycones have antimutagenic and free radical scavenging properties. The lipophilic flavone baicalein has been confirmed to be the most powerful antimutagen among the compounds tested. |
| Databáze: | OpenAIRE |
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