Time Course of Functional Recovery in Takotsubo (Stress) Cardiomyopathy: A Serial Speckle Tracking Echocardiography and Electrocardiography Study
| Autor: | Mi Rae Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Ejection fraction Cardiac cycle medicine.diagnostic_test business.industry Cardiomyopathy Speckle tracking echocardiography medicine.disease Functional recovery Electrocardiography Stress cardiomyopathy Echocardiography Internal medicine T wave Time course medicine Cardiology Radiology Nuclear Medicine and imaging Original Article cardiovascular diseases Takotsubo cardiomyopathy Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Cardiovascular Imaging |
| ISSN: | 2586-7296 2586-7210 |
| Popis: | Background Although rapid recovery of cardiac contraction is a hallmark of Takotsubo cardiomyopathy (TTC), the time course of recovery is still ill-defined. We aimed to investigate the time course of left ventricular (LV) functional recovery using 2D speckle tracking echocardiography and electrocardiography (ECG). Methods Thirty-two consecutive patients (65 ± 16 years, 26 women) with TTC were prospectively recruited. ECG and echocardiography were performed at baseline (No. 1), before discharge (No. 2), and at 1 week (No. 3) and 5 weeks (No. 4) after discharge. Echocardiographic images and ECGs were analyzed to measure ejection fraction (LVEF), global and regional longitudinal strain (GLS, RLS), and T wave inversion (TWI) scores. Results At baseline, LVEF, GLS, and TWI score were 39 ± 8.8%, -11 ± 4.3%, and 1.8 ± 3.0, respectively. Both LVEF and GLS continued to improve from baseline at the No. 2, No. 3, and No. 4 timepoints (49 ± 9.3%, 56 ± 7.5%, 58 ± 6.8%, respectively, for LVEF and -15 ± 4.2%, -17 ± 3.9%, -19 ± 3.4%, respectively, for GLS). TWI score was decreased at the No. 3 ECG relative to baseline and then increased (No. 2: -2.5 ± 3.0, No. 3: -2.9 ± 5.2, No. 4: -0.3 ± 4.4). In the apical subgroup, the reverse base-to-apex gradient of RLS had disappeared by the No. 3 echocardiography. Conclusions Contractile function as assessed by LVEF and GLS recovered continuously in patients with TTC throughout the acute and subacute phases, with rapid recovery in the acute phase. Negative T wave progressed during the acute phase and recovered more slowly during the subacute phase. |
| Databáze: | OpenAIRE |
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