Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-γ-linolenic and eicosapentaenoic acid in plasma of adult men
| Autor: | Sheila M. Innis, Y. Angela Liou |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Linolenic acid Linoleic acid Clinical Biochemistry Linoleic Acid chemistry.chemical_compound 8 11 14-Eicosatrienoic Acid Essential fatty acid Eicosanoic Acids Humans Food science Unsaturated fatty acid Randomized Controlled Trials as Topic chemistry.chemical_classification Arachidonic Acid Cross-Over Studies alpha-Linolenic acid food and beverages Cell Biology Middle Aged Eicosapentaenoic acid Diet Biochemistry chemistry Docosahexaenoic acid lipids (amino acids peptides and proteins) Arachidonic acid |
| Zdroj: | Prostaglandins, Leukotrienes and Essential Fatty Acids. 80:201-206 |
| ISSN: | 0952-3278 |
| DOI: | 10.1016/j.plefa.2009.02.003 |
| Popis: | High intakes of linoleic acid (LA,18:2n-6) have raised concern due to possible increase in arachidonic acid (ARA, 20:4n-6) synthesis, and inhibition of alpha linolenic acid (ALA, 18:3n-3) desaturation to eicosapentaenoic (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). In healthy men, 10.5% energy compared to 3.8% energy LA with 1% energy ALA increased plasma phospholipid LA and 20:2n-6, the elongation product of LA, and decreased EPA, with no change in ARA. However, LA was inversely related to ARA at both 10.5% energy and 3.8% energy LA, (r=-0.761, r=-0.817, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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