Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease
| Autor: | Andro Košec, Orjena Žaja, Boris Jelavić, Tomislav Baudoin, Filip Matovinović |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
obesity Nausea Laryngoscopy pediatric gastroesophageal reflux disease lcsh:Medicine 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Internal medicine medicine diagnostics 030223 otorhinolaryngology Asthma Original Research Framingham Risk Score medicine.diagnostic_test business.industry screening lcsh:R medicine.disease lcsh:Otorhinolaryngology lcsh:RF1-547 Chronic cough Otorhinolaryngology GERD medicine.symptom Esophageal pH monitoring business Cohort study |
| Zdroj: | International Archives of Otorhinolaryngology International Archives of Otorhinolaryngology, Volume: 24, Issue: 4, Pages: 472-476, Published: 16 NOV 2020 International Archives of Otorhinolaryngology v.24 n.4 2020 Fundação Otorrinolaringologia (FORL) instacron:FORL International Archives of Otorhinolaryngology, Vol 24, Iss 04, Pp e472-e476 (2020) |
| ISSN: | 1809-9777 |
| Popis: | Introduction Current practice guidelines in gastroesophageal reflux disease (GERD) often require invasive diagnostic testing. Objective The aim of the present study was to evaluate the significance of extra-esophageal symptoms and reliability of a screening risk score that is simple to use. Methods A longitudinal retrospective single-institution cohort study. Setting: A university clinical hospital tertiary referral center. The present study enrolled pediatric patients with symptoms suggestive of GERD: epigastric pain, occasional nausea, regurgitation, tasting acid in the oral cavity, chronic cough, hoarseness of voice, frequent throat clearing. The patients underwent 24-hour esophageal pH monitoring and fiber-optic laryngoscopy. The correlations between the local findings, anamnestic and objective measurement data were analyzed. Results The present study evaluated 89 pediatric patients. Patients with asthma presented significantly more often with adjoining gastrointestinal symptoms (p = 0.0472). Patients that were obese were linked to a higher rate of reports of gastrointestinal symptoms (p = 0.0495). After the patients had been assigned to newly developed risk groups, obesity showed to be significantly more frequent in patients placed in higher risk groups (p Conclusion Patients with leading symptoms of asthma presented significantly more often with adjoining gastrointestinal symptoms. Obesity showed to be significantly more frequent in patients placed in higher risk groups for a positive GERD diagnosis. |
| Databáze: | OpenAIRE |
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