Persistent Hypoglycemia Induced by Long-acting Insulin Degludec
| Autor: | Shuhei Nakanishi, Kenji Kohara, Fuminori Tatsumi, Tomohiko Kimura, Kohei Kaku, Masashi Shimoda, Hideaki Kaneto, Takashi Kusano, Atsushi Obata, Yukino Katakura, Tomoatsu Mune |
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| Rok vydání: | 2022 |
| Předmět: |
Blood Glucose
Male Insulin degludec medicine.medical_specialty Long acting insulin Insulin Glargine Hypoglycemia Internal medicine Internal Medicine medicine Humans Hypoglycemic Agents Glycated Hemoglobin business.industry Albumin General Medicine Middle Aged medicine.disease Severe hypoglycemia Insulin Long-Acting Exogenous insulin Diabetes Mellitus Type 1 Endocrinology Diabetes Mellitus Type 2 Intravenous glucose business |
| Zdroj: | Internal Medicine. 61:861-864 |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | A 58-year-old Japanese man was brought to the emergency room due to disturbance of consciousness. He regained consciousness on the day of admission and started taking hospital meals, but he needed intravenous glucose administration for eight days. The total amount of glucose administration was 4,464 g. It took over three weeks for exogenous insulin to be almost undetectable. While degludec binds to albumin and exerts glucose-lowering effects for a long time, the above-mentioned period of three weeks was consistent with the half-life of albumin. Hypoglycemia induced by massive dose of insulin degludec is persistent and prominent. |
| Databáze: | OpenAIRE |
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