Molecularly imprinted polymer nanomaterials and nanocomposites: atom-transfer radical polymerization with acidic monomers
| Autor: | Bernadette Tse Sum Bui, Karsten Haupt, Zeynep Adali-Kaya, Aude Falcimaigne-Cordin |
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| Přispěvatelé: | Génie Enzymatique et Cellulaire (GEC), Université de Technologie de Compiègne (UTC)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Atom-transfer radical-polymerization
Radical polymerization Molecularly imprinted polymer 02 engineering and technology General Medicine General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences Nanomaterials chemistry.chemical_compound Living free-radical polymerization Monomer chemistry Polymer chemistry Living polymerization [CHIM]Chemical Sciences 0210 nano-technology Molecular imprinting |
| Zdroj: | Angewandte Chemie International Edition Angewandte Chemie International Edition, Wiley-VCH Verlag, 2015, 54, pp.192-195 |
| ISSN: | 1433-7851 1521-3773 |
| Popis: | International audience; Molecularly imprinted polymers (MIPs) are artificial receptors which can be tailored to bind target molecules specifically. A new method, using photoinitiated atom-transfer radical polymerization (ATRP) for their synthesis as monoliths, thin films and nanoparticles is described. The synthesis takes place at room temperature and is compatible with acidic monomers, two major limitations for the use of ATRP with MIPs. The method has been validated with MIPs specific for the drugs testosterone and S-propranolol. This study considerably widens the range of functional monomers and thus molecular templates which can be used when MIPs are synthesized by ATRP, as well as the range of physical forms of these antibody mimics, in particular films and lithographic patterns, and their post-functionalization from living chain-ends. |
| Databáze: | OpenAIRE |
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