Prophylaxis against bone loss in Kock reservoir patients with reduced glomerular filtration rate
| Autor: | Elisabet Lindholm, Harriet Törnqvist, David Pazooki, Dan Mellström, Hans Herlitz, Göran Lindstedt, Olof Jonsson |
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| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Urology Osteoporosis Colonic Pouches Parathyroid hormone Renal function Bone Density Internal medicine medicine Humans Cystatin C Dual-energy X-ray absorptiometry Cholecalciferol Bone mineral biology medicine.diagnostic_test business.industry Urinary Reservoirs Continent Middle Aged medicine.disease Cystatins Endocrinology Nephrology Dietary Supplements Osteocalcin biology.protein Calcium Female business Continent Urinary Diversion Glomerular Filtration Rate |
| Zdroj: | Scandinavian Journal of Urology and Nephrology. 39:200-205 |
| ISSN: | 1651-2065 0036-5599 |
| DOI: | 10.1080/00365590510007829 |
| Popis: | Objective We investigated whether treatment with calcium carbonate and vitamin D3 can improve the bone mineral content of patients with ileal reservoirs for continent urinary diversion and a reduced glomerular filtration rate (GFR). Material and methods Twenty-six patients with Kock reservoirs were included in the study. Bone mineralization was determined using dual-energy X-ray absorptiometry. Kidney function was estimated from Cr–EDTA clearance and serum cystatin C concentration. Osteocalcin and parathyroid hormone in serum were also measured. Patients with reduced GFR were treated with calcium carbonate and vitamin D3 perorally. Results Bone mineral density in the femur neck and hip increased in the treatment group, as reflected by an improved T score. Conclusion Patients with ileal reservoirs for continent urinary diversion and reduced kidney function should be supplemented with calcium carbonate and vitamin D3 in order to reduce the long-term risk of osteoporosis. |
| Databáze: | OpenAIRE |
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