Targeting Metastatic and Advanced Breast Cancer
Autor: | Melody A. Cobleigh, Susan Moore |
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Rok vydání: | 2007 |
Předmět: |
Oncology
medicine.medical_specialty Chemotherapy Oncology (nursing) business.industry Advanced breast medicine.medical_treatment Cancer Antineoplastic Agents Breast Neoplasms medicine.disease Metastatic breast cancer Targeted therapy Regimen Clinical research Quality of life Internal medicine Quality of Life medicine Humans Female Neoplasm Metastasis business |
Zdroj: | Seminars in Oncology Nursing. 23:37-45 |
ISSN: | 0749-2081 |
Popis: | Objectives To review the chemotherapy and targeted biologic options for treatment of advanced and metastatic breast cancer. Data Sources Clinical and research articles and textbook chapters. Conclusion Recent clinical research has led to the use of novel targeted therapies in the management of locally advanced and metastatic breast cancer. Although metastatic breast cancer remains incurable, increases in disease-free and overall survival has been achieved. Implications for Nursing Practice Recent advances in the biological targeted therapies against Her2/ neu , VEGF, and EGFR are now either approved therapies or are in the final stages of clinical testing. Oncology nurses can help decrease toxicities and maintain better QOL by fully understanding the mechanism of action of the drugs, expected side effects, and anticipated response to the novel regimen. |
Databáze: | OpenAIRE |
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