Evolution of Conus peptide toxins: Analysis of Conus californicus Reeve, 1844
| Autor: | Jason S. Biggs, Maren Watkins, Estuardo López-Vera, Baldomero M. Olivera, Johanna Bernáldez, Sean Christensen, John Paul Ownby, Nicolas Puillandre, Patrice Showers Corneli, Karla Juarez Moreno, Alexei F. Licea-Navarro |
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| Rok vydání: | 2010 |
| Předmět: |
DNA
Complementary animal structures Molecular Sequence Data Conus californicus Venom DNA Mitochondrial Article Cone snail Evolution Molecular Sequence Analysis Protein Phylogenetics RNA Ribosomal 16S Conus Genetics Animals Gene family Amino Acid Sequence Conotoxin Cloning Molecular Molecular Biology Phylogeny Ecology Evolution Behavior and Systematics biology Conus Snail biology.organism_classification Molecular biology RNA Ribosomal Evolutionary biology Predatory Behavior Conotoxins Protein Processing Post-Translational |
| Zdroj: | Molecular Phylogenetics and Evolution. 56:1-12 |
| ISSN: | 1055-7903 |
| Popis: | Conus species are characterized by their hyperdiverse toxins, encoded by a few gene superfamilies. Our phylogenies of the genus, based on mitochondrial genes, confirm previous results that C. californicus is highly divergent from all other species. Genetic and biochemical analysis of their venom peptides comprise the fifteen most abundant conopeptides and over 50 mature cDNA transcripts from the venom duct. Although C. californicus venom retains many of the general properties of other Conus species, they share only half of the toxin gene superfamilies found in other Conus species. Thus, in these two lineages, approximately half of the rapidly diversifying gene superfamilies originated after an early Tertiary split. Such results demonstrate that, unlike endogenously acting gene families, these genes are likely to be significantly more restricted in their phylogenetic distribution. In concordance with the evolutionary duistance of C. californicus from other species, there are aspects of prey-capture behavior and prey preferences of this species that diverges significantly from all other Conus. |
| Databáze: | OpenAIRE |
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