Pharmacist Intervention for Blood Pressure Control in Patients with Diabetes and/or Chronic Kidney Disease

Autor: David L. Hahn, James D. Hoehns, Timothy J. Ives, Liz Uribe, Barry L. Carter, Christopher S. Coffey, Maxwell D. Anderegg, Tyler H. Gums, Eric J. MacLaughlin, Oralia V. Bazaldua
Jazyk: angličtina
Rok vydání: 2018
Předmět:
ISSN: 0093-5077
Popis: OBJECTIVES: The objectives of this study were to 1) determine if hypertensive patients with comorbid diabetes mellitus (DM) and/or chronic kidney disease (CKD) receiving a pharmacist intervention had a greater reduction in mean blood pressure (BP) and improved BP control at 9 months compared to those receiving usual care and 2) compare Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-7) guideline and 2014 guideline (JNC-8) BP control rates in patients with DM and/or CKD. METHODS: This cluster, randomized trial included 32 medical offices in 15 states. Clinical pharmacists made treatment recommendations to physicians at intervention sites. This post-hoc analysis evaluated mean BP and BP control rates in the intervention and control groups. MAIN RESULTS: The study included 335 patients (227 intervention, 108 control) when mean BP and control rates were evaluated by JNC-7 inclusion and control criteria. When JNC-8 inclusion and control criteria were applied, 241 patients (165 intervention, 76 control) remained and were included in the analysis. The pharmacist-intervention group had significantly greater mean SBP reduction compared to usual care at 9 months (8.64 mm Hg [95% Confidence interval (CI)= −12.8, −4.49, p
Databáze: OpenAIRE