Lung Volume Reduction Surgery in Patients with Heterogenous Emphysema: Selecting Perspective

Autor: Dong Khac Hung, Nguyen Viet Nhung, Pham Ngoc Hung, Ta Ba Thang, Nguyen Van Nam, Chu Dinh Toi, Nguyen Truong Giang, Trung Nguyen Ngoc, Nguyen Duy Bac
Rok vydání: 2019
Předmět:
Zdroj: Open Access Macedonian Journal of Medical Sciences
Open Access Macedonian Journal of Medical Sciences, Vol 7, Iss 24 (2019)
Open Access Macedonian Journal of Medical Sciences; Vol. 7 No. 24 (2019): Dec 30 (Basic and Clinical Medical Researches in Vietnam); 4389-4392
ISSN: 1857-9655
Popis: BACKGROUND: Lung volume reduction surgery (LVRS) was introduced to alleviate clinical conditions in selected patients with heterogenous emphysema. Clarifying the most suitable patients for LVRS remained unclear. AIM: This study was undertaken to specifically analyze the preoperative factor affecting to LVRS. METHODS: The prospective study was conducted at 103 Military Hospital between July 2014 and April 2016. Severe heterogenous emphysema patients were selected to participate in the study. The information, spirometry, and body plethysmographic pulmonary function tests in 31 patients who underwent LVRS were compared with postoperative outcomes (changing in FEV1 and CAT scale). RESULTS: Of the 31 patients, there was statistically significant difference in the outcome of functional capacity, lung function between two groups (FEV1 ≤ 50% and > 50%) (∆FEV1: 22.46 vs 18.32%; p = 0.042. ∆CAT: 6.85 vs 5.07; p = 0.048). Changes of the FEV1 and CAT scale were no statistically significant differences in three groups residual volume. Patients with total lung capacity < 140% had more improved than others (∆FEV1: 23.81 vs 15.1%; p = 0.031). CONCLUSION: Preoperative spirometry and body plethysmographic pulmonary function tests were useful measures to selected severe heterogenous emphysema patients for LVRS. Patients with FEV1 ≤ 50%, TLC in the range of 100-140% should be selected.
Databáze: OpenAIRE