Surgery in patients with congenital factor VII deficiency - a single center study
| Autor: | Anna Oses-Szczepanik, Andrzej Misiak, W. Dąbrowski, Andrzej B. Szczepanik, Adam Wiszniewski, Konrad Pielaciński |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Factor VII Deficiency medicine.medical_treatment Blood Loss Surgical Hemorrhage Factor VIIa Single Center Hemorrhagic disorder Young Adult 03 medical and health sciences Postoperative Complications 0302 clinical medicine Preoperative Care Varicose veins Humans Medicine Aged Coagulants business.industry Thyroidectomy General Medicine Perioperative Middle Aged medicine.disease Recombinant Proteins Surgery Inguinal hernia Treatment Outcome 030220 oncology & carcinogenesis Hemostasis Female Vitamin K Deficiency Intraoperative Period medicine.symptom business 030215 immunology |
| Zdroj: | Polish Journal of Surgery. 90:1-5 |
| ISSN: | 2299-2847 0032-373X |
| Popis: | Introduction: Congenital factor VII deficiency is a rare hemorrhagic disorder inherited in an autosomal recessive pattern. Surgical treatment with insufficient diathesis correction is burdened with high risk of bleeding complications. The aim of the study was evaluation of the surgical outcome in patients with congenital factor VII deficiency and assessment of the efficacy and safety of recombinant activated factor VII (rFVIIa) used for perioperative hemostatic coverage in our two schemas of substitutive therapy. Material and methods: In the years 2002-2017 a total of 22 patients with congenital factor VII deficiency were subjected to surgery. Substitution therapy relied on rFVIIa used in two schemas. One involved 15 patients with factor VII activity of |
| Databáze: | OpenAIRE |
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