Clinical characteristics of 967 children with pertussis: a single-center analysis over an 8-year period in Beijing, China
| Autor: | Tiegeng Li, Xiaoying Wang, Limin Kang, Xinlin Hou, Wenpeng Wang, Li Li, Fei Xiao, Rong Mi, Jin Fu, Xiaodai Cui, Huixue Jia |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Male Bordetella pertussis Pediatrics medicine.medical_specialty Adolescent Whooping Cough Atelectasis macromolecular substances Hypoxemia Medicine Humans Risk factor Child Children Retrospective Studies biology Clinical characteristics business.industry Incidence (epidemiology) Infant General Medicine medicine.disease biology.organism_classification Hospitals Pediatric Hospitalization Pneumonia Infectious Diseases Beijing Child Preschool Vomiting Original Article Female Age of onset medicine.symptom business |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases |
| ISSN: | 1435-4373 0934-9723 |
| Popis: | The purpose of this study is to understand children’s clinical characteristics with pertussis and analyze risk factors on critical pertussis patients. Demographic data from patients with pertussis at Children’s Hospital affiliated to the Capital Institute of Pediatrics between March 2011 and December 2018 were collected. We retrospectively gathered more information with the positive exposure, vaccination, antibiotic usage before diagnosis, clinical manifestation, laboratory tests, therapy, and complications for hospitalized children. We divided the patients into severe and non-severe groups, comparing related factors and clinical characteristics among each group. In particular, we summarize the clinical features of the severe patients before aggravation. A total of 967 pertussis cases were diagnosed, of which 227 were hospitalized. The onset age younger than 3 months old accounted for the highest proportion, and 126 patients received hospitalization. For those patients, the incidence of post-tussive vomiting, paroxysmal cyanosis, post-tussive heart rate decrease, hypoxemia, severe pneumonia, and mechanical ventilation was significantly higher than that in the ≥ 3-month-old group (p |
| Databáze: | OpenAIRE |
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