A 12-month Feeding Study of Reproduction/Development in Rats Fed Meat/Milk Powder Supplemented Diets Derived from the Progeny of Cloned Cattle Produced by Somatic Cell Nuclear Transfer
| Autor: | Yoshihiko Ito, Makiko Yamaguchi, Shinya Watanabe, Masaya Itoh |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Male
Nuclear Transfer Techniques Meat Time Factors Animal feed Cloning Organism media_common.quotation_subject Motor Activity Urinalysis Biology Eating Animal science Animals Motor activity Food science Chronic toxicity Organ weight media_common Cloning Blood biochemistry Reproduction Body Weight food and beverages Animal Feed Rats Milk Dietary Supplements Somatic cell nuclear transfer Cattle Female Animal Science and Zoology Growth and Development Powders Blood Chemical Analysis |
| Zdroj: | Journal of Reproduction and Development. 54:321-334 |
| ISSN: | 1348-4400 0916-8818 |
| DOI: | 10.1262/jrd.20060 |
| Popis: | The present 12-month feeding study was carried out with rat groups fed a diet supplemented with meat or milk (meat/milk) derived from the progeny of clones produced by somatic cell nuclear transfer (SCNT) technology. It was conducted to obtain data concerning the chronic toxicities of these edible products during the process of development and reproduction in rats fed such products. The rats were subjected to clinical observations for general health condition and examinations such as sensory/reflex function, grip strength, motor activity, body weight, food consumption, ophthalmology and urinalysis. Moreover, sexually matured rats fed the test diets were mated and examined for items such as the reproductive performances of the dams and health of their pups. After the feeding period, factors related to rat health status, based on the findings for hematology, blood biochemistry, necropsy, organ weight and histology, were examined. There were no biologically significant differences in these factors between the rat groups fed meat/milk powder supplemented diets derived from the progeny and those fed meat/milk powder supplemented diets derived from conventionally bred cattle. Therefore, the present chronic toxicity study suggests that meat and milk derived from the progeny of SCNT cattle might be equivalent to those derived from conventionally bred cattle in use as dietary supplements for rats. |
| Databáze: | OpenAIRE |
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