Case Report: Two Cases of Acute Q Fever from the Same Family Who Returned from Malawi to Japan
| Autor: | Kayoko Hayakawa, Keiji Nakamura, Satoshi Kutsuna, Maki Nagashima, Takato Nakamoto, Hiroko Toriniwa, Tomoyoshi Komiya, Toshihiro Matsui, Norio Ohmagari, Kei Yamamoto |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
DNA Bacterial Male Malawi medicine.medical_specialty 030231 tropical medicine Q fever 03 medical and health sciences 0302 clinical medicine Japan Virology Internal medicine Epidemiology medicine Humans Family biology Dry cough business.industry Articles Coxiella burnetii biology.organism_classification medicine.disease Antibodies Bacterial Convalescent phase Infectious Diseases Immunoglobulin M Child Preschool Immunoglobulin G Acute Disease Female Parasitology Q Fever Travel-Related Illness business |
| Zdroj: | Am J Trop Med Hyg |
| ISSN: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.19-0544 |
| Popis: | In July 2018, acute Q fever (AQF) was diagnosed in two Japanese individuals from the same family. They returned to Japan from Malawi, where the epidemiology of AQF is unknown. A child presented to the hospital with high-grade fever without any symptoms, and a mother presented with fever and dry cough. Paired serum antiphase Ⅱ IgM and IgG significantly elevated in the convalescent phase in both cases. Coxiella burnetii gene (IS1111) was detected from the mother’s blood sample. They had no reported direct animal contact, but the onset of symptoms coincided with the dry season in Malawi, which may have facilitated environmental dispersal. These cases may serve as an alert for high-risk people to possible AQF spread and underdiagnosis in Malawi. |
| Databáze: | OpenAIRE |
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