Triple Stimulation Technique in Amyotrophic Lateral Sclerosis
| Autor: | Yue Wang, Li-ying Cui, Han Wang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Adolescent Physiology medicine.medical_treatment Neural Conduction 050105 experimental psychology Upper Extremity Young Adult 03 medical and health sciences 0302 clinical medicine Physiology (medical) medicine Humans 0501 psychology and cognitive sciences Prospective Studies Amyotrophic lateral sclerosis Child Aged Motor Neurons Stimulation technique business.industry Upper motor neuron Electrodiagnosis Amyotrophic Lateral Sclerosis 05 social sciences Middle Aged Evoked Potentials Motor bacterial infections and mycoses medicine.disease Transcranial Magnetic Stimulation Electric Stimulation Transcranial magnetic stimulation medicine.anatomical_structure Neurology Female Neurology (clinical) business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Neurophysiology. 36:87-92 |
| ISSN: | 0736-0258 |
| Popis: | To identify upper motor neuron (UMN) dysfunction using the triple stimulation technique (TST) in amyotrophic lateral sclerosis (ALS).Fifty ALS and 42 non-ALS patients were examined clinically, using conventional transcranial magnetic stimulation and TST.For ALS patients presenting with UMN in tested limb, the TST amplitude ratio was abnormal in 25 of 28 patients (89.3%). For ALS patients without UMN signs, 6 of 22 patients (27.3%) had an abnormal TST ratio. When clinical signs were not present, both abnormal resting motor threshold and TST indicated a UMN involvement. In non-ALS patients with central motor conduction disorders, the percentage of patients with an abnormal TST was higher for those presenting with clinical UMN signs (9/12, 75.0%) than for those without these signs (1/8, 12.5%).Triple stimulation technique appears to be an accurate, early measure for detecting clinical and subclinical UMN abnormalities in ALS. Triple stimulation technique could also be useful to investigate central motor conduction abnormalities in other disorders. |
| Databáze: | OpenAIRE |
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