Combined photothermal–photodynamic therapy by indocyanine green loaded polydopamine nanoparticles enhances anti-mammary gland tumor efficacy

Autor: Xu Liu, Na Xu, Ximing Pu, Juan Wang, Xiaoming Liao, Zhongbing Huang, Guangfu Yin
Rok vydání: 2022
Předmět:
Zdroj: Journal of Materials Chemistry B. 10:4605-4614
ISSN: 2050-7518
2050-750X
DOI: 10.1039/d2tb00565d
Popis: Various nano-targeted drug delivery systems have been developed for combined photothermal-photodynamic (PTT-PDT) treatment of tumors due to better outcomes compared with monomodality therapy. Here, we constructed a facile two-step method without core templates to obtain indocyanine green (ICG) loaded-hyaluronic acid (HA) surface-coated polydopamine nanoparticles (IIPH). The prepared nanoparticles demonstrated an excellent photothermal conversion capacity and efficient singlet oxygen production. Both
Databáze: OpenAIRE