Quantification of epicardial adipose tissue in coronary calcium score and CT coronary angiography image data sets: comparison of attenuation values, thickness and volumes
| Autor: | Filippo Cademartiri, Domenico Albano, Patrizia Toia, Emanuele Grassedonio, Erica Maffei, Alfonso Farruggia, Massimo Midiri, Ludovico La Grutta, A. Palmeri, Salvatore Vitabile, Massimo Galia |
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| Přispěvatelé: | La Grutta, L., Toia, P., Farruggia, A., Albano, D., Grassedonio, E., Palmeri, A., Maffei, E., Galia, M., Vitabile, S., Cademartiri, F., Midiri, M., Radiology & Nuclear Medicine |
| Rok vydání: | 2016 |
| Předmět: |
Male
Coronary angiography Computed Tomography Angiography Adipose tissue Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Sensitivity and Specificity 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Hounsfield scale medicine Humans Radiology Nuclear Medicine and imaging Vascular Calcification Adiposity Computed tomography angiography Full Paper medicine.diagnostic_test business.industry Reproducibility of Results Mean age General Medicine Middle Aged medicine.disease Coronary Calcium Score Adipose Tissue epicardial adipose tissue CT coronary angiography Epicardial adipose tissue Radiographic Image Interpretation Computer-Assisted Female Settore MED/36 - Diagnostica Per Immagini E Radioterapia business Nuclear medicine Pericardium Algorithms |
| Zdroj: | British Journal of Radiology, 89(1062):20150773. British Institute of Radiology |
| ISSN: | 1748-880X 0007-1285 |
| DOI: | 10.1259/bjr.20150773 |
| Popis: | The aim of the study was to compare epicardial adipose tissue (EAT) characteristics assessed with coronary calcium score (CS) and CT coronary angiography (CTCA) image data sets.In 76 patients (mean age 59 ± 13 years) who underwent CS and CTCA owing to suspected coronary artery disease (CAD), EAT was quantified in terms of density (Hounsfield units), thickness and volume. The EAT volume was extracted with a semi-automatic software.A moderate correlation was found between EAT density in CS and CTCA image data sets (-100 ± 19 HU vs -70 ± 24 HU; p 0.05, r = 0.55). The distribution of EAT was not symmetrical with a maximal thickness at the right atrioventricular groove (14.2 ± 5.3 mm in CS, 15.7 ± 5 mm in CTCA; p 0.05, r = 0.76). The EAT volume resulted as 122 ± 50 cm(3) in CS and 86 ± 40 cm(3) in CTCA (Δ = 30%, p 0.05, r = 0.92). After adjustment for post-contrast EAT attenuation difference (Δ = 30 HU), the volume was 101 ± 47 cm(3) (Δ = 17%, p 0.05, r = 0.92). Based on EAT volume median values, no differences were found between groups with smaller and larger volumes in terms of Agatston score and CAD severity.CS and CTCA image data sets may be equally employed for EAT assessment; however, an underestimation of volume is found with the latter acquisition even after post-contrast attenuation adjustment.EAT may be measured by processing either the CS or CTCA image data sets. |
| Databáze: | OpenAIRE |
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