Measurements of endothelin-1, C-reactive protein and fibrinogen plasma levels in patients with acute ischemic stroke
| Autor: | Sotirios Giannopoulos, Maria Kosmidou, A. G. Ziakas, Michail Karamouzis, Christos Savopoulos, Apostolos I. Hatzitolios |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Brain Ischemia/*blood/*diagnosis/physiopathology Up-Regulation/physiology Brain/metabolism/physiopathology/radiography Fibrinogen/analysis/*metabolism Radioimmunoassay Fibrinogen Gastroenterology Brain Ischemia Brain ischemia Predictive Value of Tests Internal medicine medicine Humans Biological Markers/analysis/blood Acute ischemic stroke Aged Aged 80 and over biology Endothelin-1 business.industry C-reactive protein Brain General Medicine Plasma levels medicine.disease Endothelin 1 Endothelin-1/analysis/*blood Surgery Up-Regulation C-Reactive Protein Neurology Predictive value of tests Acute Disease biology.protein Female Neurology (clinical) C-Reactive Protein/analysis/*metabolism business Tomography X-Ray Computed Biomarkers medicine.drug |
| Zdroj: | Neurological research. 30(7) |
| ISSN: | 0161-6412 |
| Popis: | OBJECTIVE: To assess plasma endothelin-1 (ET-1), C-reactive protein (CRP) and fibrinogen (FIB) levels in acute ischemic stroke (AIS) and explore the potential association among them. METHODS: In 23 consecutive patients with AIS diagnosed clinically and confirmed by CT brain scan, we measured plasma levels of ET-1 by radioimmunoassay, and CRP and FIB on the first and fifth days after the onset of AIS and we compared them with the levels of ten healthy volunteers in the control group. RESULTS: The mean plasma levels of ET-1 in AIS patients on the first and fifth days were respectively 19.93+/-6.72 and 16.47+/-26.3 pmol/l (p0.05) compared with 0.2+/-0.1 mg/dl in the control group (p0.05 versus mean values on the first and fifth days). A positive association was found between the plasma levels of ET-1 and CRP on the fifth day (p |
| Databáze: | OpenAIRE |
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