COVID-Associated Pulmonary Aspergillosis and Its Related Outcomes: A Single-Center Prospective Observational Study
| Autor: | Ahtesham Iqbal, Javeria Khalid, Seemal Aslam, Anam Ahtesham, Moazma Ramzan, Aftab Akhtar |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
invasive mechanical ventilation
medicine.medical_specialty Pulmonology medicine.medical_treatment Population Infectious Disease Single Center Malignancy Interquartile range Internal medicine Internal Medicine Medicine education Mechanical ventilation education.field_of_study business.industry Septic shock General Engineering covid associated pulmonary aspergillosis medicine.disease severe covid pneumonia Pneumonia outcome probable capa business Complication |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.16982 |
| Popis: | Background and objective Invasive pulmonary aspergillosis (IPA) is a frequent complication among neutropenic patients. It is increasingly being reported in critical coronavirus disease 2019 (COVID-19) patients requiring ICU admission and invasive mechanical ventilation (IMV) and is known as COVID-associated pulmonary aspergillosis (CAPA). We conducted this large prospective observational study to determine the frequency of CAPA and its outcomes in the ICU population. Methodology This was a prospective observational study. We recruited 307 reverse transcription-polymerase chain reaction (RT-PCR)-confirmed cases of severe COVID-19 pneumonia requiring IMV. We excluded those who did not require IMV or had been transferred out to other hospitals. The Chi-square test was applied to find the association between categorical variables. A p-value of |
| Databáze: | OpenAIRE |
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