Phenotypic, hormonal, and clinical characteristics of equine endocrinopathic laminitis

Autor: Martin N. Sillence, Dania Birte Reiche, Melody A. de Laat
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
medicine.medical_specialty
Hoof and Claw
040301 veterinary sciences
medicine.medical_treatment
Standard Article
030204 cardiovascular system & hematology
Endocrine System Diseases
0403 veterinary science
Cohort Studies
Foot Diseases
03 medical and health sciences
0302 clinical medicine
Endocrinology
Adrenocorticotropic Hormone
Metabolic Diseases
Internal medicine
Pituitary pars intermedia dysfunction
medicine
Hyperinsulinemia
Animals
Body Size
Insulin
Horses
Prospective Studies
Prospective cohort study
lcsh:Veterinary medicine
General Veterinary
business.industry
Horse
04 agricultural and veterinary sciences
Laminitis
medicine.disease
equine metabolic syndrome
Standard Articles
ACTH
horse
Diet
Equine metabolic syndrome
pituitary pars intermedia dysfunction
Lameness
hyperinsulinemia
lcsh:SF600-1100
Female
Horse Diseases
EQUID
business
Zdroj: Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine, Vol 33, Iss 3, Pp 1456-1463 (2019)
ISSN: 1939-1676
0891-6640
Popis: BACKGROUND: Equine endocrinopathic laminitis is common and can be associated with an underlying endocrinopathy, such as equine metabolic syndrome (EMS), pituitary pars intermedia dysfunction (PPID), pasture consumption, or any combination of these factors. OBJECTIVES: The aim of the study was to improve the risk assessment capabilities of clinicians, and to inform management strategies, for acute endocrinopathic laminitis by prospectively examining the phenotypic, hormonal, and clinical characteristics of the disease in a large cohort. ANIMALS: Privately owned horses and ponies (n = 301) of any age, sex, or breed diagnosed with laminitis by a veterinarian. A history of laminitis was acceptable. METHODS: This was a prospective cohort study. Veterinarians provided information on each case via an online questionnaire after informed consent from the animal's owner, and all data were de‐identified before analysis. Serum insulin and plasma adrenocorticotrophic hormone concentrations were measured in each case. RESULTS: Most cases were recruited in spring (109/301; 36.2%). Concurrent EMS and PPID resulted in higher basal insulin concentrations (49 [21.5‐141]; P
Databáze: OpenAIRE
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