Multi-Step Enzyme Catalysis: Biotransformations and Chemoenzymatic Synthesis

Autor: Eduardo García-Junceda
Rok vydání: 2008
Předmět:
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
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Multi-Step Enzyme Catalysis
Popis: The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.
Front Matter (pages I–XV) Chapter 1 Asymmetric Transformations by Coupled Enzyme and Metal Catalysis: Dynamic Kinetic Resolution (pages 1–19) Mahn-Joo Kim, Jaiwook Park and Yoon Kyung Choi Chapter 2 Chemoenzymatic Routes to Enantiomerically Pure Amino Acids and Amines (pages 21–39) Nicholas J. Turner Chapter 3 Oxidizing Enzymes in Multi-Step Biotransformation Processes (pages 41–60) Stephanie G. Burton and Marilize le Roes-Hill Chapter 4 Dihydroxyacetone Phosphate-Dependent Aldolases in the Core of Multi-Step Processes (pages 61–81) Laura Iturrate and Eduardo García-Junceda Chapter 5 Multi-Enzyme Systems for the Synthesis of Glycoconjugates (pages 83–107) Birgit Sauerzapfe and Lothar Elling Chapter 6 Enzyme-Catalyzed Cascade Reactions (pages 109–135) Roger A. Sheldon Chapter 7 Multi-Modular Synthases as Tools of the Synthetic Chemist (pages 137–158) Michael D. Burkart and Junhua Tao Chapter 8 Modifying the Glycosylation Pattern in Actinomycetes by Combinatorial Biosynthesis (pages 159–198) José A. Salas and Carmen Méndez Chapter 9 Microbial Production of DNA Building Blocks (pages 199–211) Jun Ogawa, Nobuyuki Horinouchi and Sakayu Shimizu Chapter 10 Combination of Biocatalysis and Chemical Catalysis for the Preparation of Pharmaceuticals Through Multi-Step Syntheses (pages 213–233) Vicente Gotor-Fernández, Rosario Brieva and Vicente Gotor SummaryPDF(237K)ReferencesServicio de Enlaces CSICYou have free access to this contentIndex (pages 235–241)
Databáze: OpenAIRE