A review on the traditional uses, phytochemistry, and pharmacological activities of clove basil (Ocimum gratissimum L.)
| Autor: | Eziuche Amadike Ugbogu, Chibuike Ibe, Ositadinma Chinyere Ugbogu, Victor Chibueze Ude, C.N. Ekweogu, Okezie Emmanuel, Miracle Ebubechi Uche, Grace Oka Agi, Rachel Oluchukwu Nnanna |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
H1-99
Multidisciplinary Traditional uses Science (General) Traditional medicine biology Rosmarinic acid Ocimum gratissimum Phytochemicals biology.organism_classification Essential oil Eugenol Social sciences (General) chemistry.chemical_compound Q1-390 Pharmacological activities chemistry Chlorogenic acid Caffeic acid Carvacrol Gallic acid Ellagic acid |
| Zdroj: | Heliyon, Vol 7, Iss 11, Pp e08404-(2021) |
| ISSN: | 2405-8440 |
| Popis: | In traditional medicine, Ocimum gratissimum (scent leaf) is used in the treatment of various diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and bacterial infections. The present study reviewed the phytochemicals, essential oils, and pharmacological activities of O. gratissimum. The bioactive compounds extracted from O. gratissimum include phytochemicals (oleanolic acid, caffeic acid, ellagic acid, epicatechin, sinapic acid, rosmarinic acid, chlorogenic acid, luteolin, apigenin, nepetoidin, xanthomicrol, nevadensin, salvigenin, gallic acid, catechin, quercetin, rutin, and kaempfero) and essential oils (camphene, β-caryophyllene, α- and β-pinene, α-humulene, sabinene, β-myrcene, limonene, 1,8-cineole, trans-β-ocimene, linalool, α- and δ-terpineol, eugenol, α-copaene, β-elemene, p-cymene, thymol, and carvacrol). Various in vivo and in vitro studies have shown that O. gratissimum and its bioactive constituents possess pharmacological properties such as antioxidant, anti-inflammatory, anticancer, hepatoprotective, antidiabetic, antihypertensive, antidiarrhoeal, and antimicrobial properties. This review demonstrated that O. gratissimum has a strong preventive and therapeutic effect against several diseases. The effectiveness of O. gratissimum to ameliorate various diseases may be attributed to its antimicrobial and antioxidant properties as well as its capacity to improve the antioxidant systems. However, despite the widespread pharmacological activities of O. gratissimum, further experiments in human clinical trial studies are needed to establish effective and safe doses for the treatment of various diseases. |
| Databáze: | OpenAIRE |
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