Developmental outcome of extremely preterm infants is improved after less invasive surfactant application: Developmental outcome after LISA
| Autor: | Bernhard Roth, Alexander Broer, Egbert Herting, Christian Wieg, Wolfgang Göpel, Norbert Teig, Thomas Höhn, Katrin Mehler, Claudia Roll, Angela Kribs, Peter Jahn, Jeremy Franklin, Lars Welzing, Marc Hoppenz, Matthias Vochem, Christoph Bührer |
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| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Breastfeeding Less invasive Surface-Active Agents 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Intensive care Humans Medicine 030212 general & internal medicine Mental development index Psychomotor learning business.industry Confounding Infant Newborn Infant Gestational age Pulmonary Surfactants General Medicine Respiration Artificial Treatment Outcome Infant Extremely Premature Pediatrics Perinatology and Child Health business Neurocognitive |
| Zdroj: | Acta Paediatrica. 110:818-825 |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/apa.15565 |
| Popis: | AIM The aim of this study was to evaluate neurocognitive outcome at 24 months of corrected age after less invasive surfactant application (LISA) in preterm infants born at 23-26 weeks of gestational age. METHODS Surviving participants of a LISA trial conducted in 13 German level III neonatal intensive care units were reviewed for assessment of developmental outcome, hearing and vision problems, growth and rehospitalisation days. Maternal depression, breastfeeding rates and socio-economic factors were evaluated as potentially confounding factors. RESULTS In total, 156/182 infants took part in the study, 78 had received surfactant via LISA and 78 via endotracheal intubation. 22% of LISA infants compared to 42% of intubated infants had a psychomotor development index (PDI) |
| Databáze: | OpenAIRE |
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