Emergence of an abstract categorical code enabling the discrimination of temporally structured tactile stimuli
| Autor: | Román Rossi-Pool, Ranulfo Romo, Antonio Zainos, Manuel Barquín Álvarez, Néstor Parga, Emilio Salinas, J. D. Vergara |
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| Přispěvatelé: | UAM. Departamento de Física Teórica |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
media_common.quotation_subject Decision Making Sensory system Pattern discrimination Stimulus (physiology) Somatosensory system Tactile stimuli Judgment 03 medical and health sciences Discrimination Psychological 0302 clinical medicine Memory Perception Reaction Time Animals Categorical code Categorical variable media_common Communication Multidisciplinary Working memory business.industry Motor Cortex Física Macaca mulatta Behaving monkeys Somatosensory cortex 030104 developmental biology PNAS Plus Pattern Recognition Physiological Dorsal premotor cortex Single-Cell Analysis business Psychology Neural coding 030217 neurology & neurosurgery Cognitive psychology |
| Zdroj: | Biblos-e Archivo. Repositorio Institucional de la UAM instname |
| Popis: | The problem of neural coding in perceptual decision making revolves around two fundamental questions: (i) How are the neural representations of sensory stimuli related to perception, and (ii) what attributes of these neural responses are relevant for downstream networks, and how do they influence decision making? We studied these two questions by recording neurons in primary somatosensory (S1) and dorsal premotor (DPC) cortex while trained monkeys reported whether the temporal pattern structure of two sequential vibrotactile stimuli (of equal mean frequency) was the same or different. We found that S1 neurons coded the temporal patterns in a literal way and only during the stimulation periods and did not reflect the monkeys' decisions. In contrast, DPC neurons coded the stimulus patterns as broader categories and signaled them during the working memory, comparison, and decision periods. These results show that the initial sensory representation is transformed into an intermediate, more abstract categorical code that combines past and present information to ultimately generate a perceptually informed choice This work was supported in part by the Dirección de Asuntos del Personal Académico de la Universidad Nacional Autónoma de México and Consejo Nacional de Ciencia y Tecnología (R.R.) and Grant FIS2015-67876-P (to N.P.) |
| Databáze: | OpenAIRE |
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