Does Diagnostic Coronary Angiography Induce Significant Coronary Microembolization in Stable, Ischemic Patients? A Prospective Study

Autor: Evangelia Karvouni, Demosthenes G. Katritsis, Alexander Haliassos, Eleftherios Giazitzoglou, George Paxinos, Socrates Korovesis
Rok vydání: 2006
Předmět:
Zdroj: Journal of Interventional Cardiology. 19:346-349
ISSN: 1540-8183
0896-4327
DOI: 10.1111/j.1540-8183.2006.00159.x
Popis: Background: Although microembolization during percutaneous coronary interventions is a frequent event, the extent of possible microembolization during diagnostic coronary angiography is unknown. The aim of the study was to investigate whether diagnostic coronary angiography results in coronary microembolization and consequent subtle, subclinical myocardial necrosis with enzyme elevations. Methods: Fifty-three consecutive patients underwent diagnostic coronary angiography due to inducible ischemia. Creatine kinase MB isoenzyme (CK MB) and cardiac troponin I (cTnI) were used as sensitive surrogate markers of myocardial necrosis. Serial measurements, before, and 6 and 24 hours following a diagnostic procedure, were performed. Results: Baseline cTnI was below the limits of detection in all patients (
Databáze: OpenAIRE