Treatment of a Full-Thickness Burn Injury With NovoSorb Biodegradable Temporizing Matrix and RECELL Autologous Skin Cell Suspension: A Case Series
| Autor: | Kenneth W. Larson, Cindy L. Austin, Simon Thompson |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Polyurethanes Biocompatible Materials Case Reports Transplantation Autologous Disease course Full thickness burn Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Graft take Humans Medicine Severe burn In patient Skin Artificial Wound Healing integumentary system business.industry Rehabilitation 030208 emergency & critical care medicine Skin Transplantation Middle Aged Combined Modality Therapy Surgery Transplantation Skin cell Emergency Medicine Female Burns business Wound healing |
| Zdroj: | Journal of Burn Care & Research: Official Publication of the American Burn Association |
| ISSN: | 1559-0488 1559-047X |
| DOI: | 10.1093/jbcr/irz179 |
| Popis: | Dermal substitutes coupled with split thickness skin graft are the primary method of treating most severe full-thickness burns particularly when there is a lack of healthy donor skin. Although dermal replacements optimize functional and aesthetic outcomes in patients, the risk of infection and the amount of time required to process most dermal substitutes delay treatment potentially compromising graft take and the overall healing process. The purpose of this case series is to describe the treatment course of patients with severe burn injuries using a novel synthetic Biodegradable Temporizing Matrix (NovoSorb BTM) in conjunction with RECELL Autologous Cell Harvesting Device, a new methodology allowing for a timely point-of-care preparation of an autologous skin cell suspension in combination with a 3:1 split-thickness skin graft. To the best of our knowledge, this is the first reported case series to describe the treatment algorithm and clinical outcomes of deep full-thickness burns utilizing BTM in conjunction with RECELL ASCS. |
| Databáze: | OpenAIRE |
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