3D magnetic resonance fingerprinting with quadratic RF phase

Autor: Rasim Boyacioğlu, Xin Yu, Debra McGivney, Dan Ma, Mark A. Griswold, Charlie Wang
Rok vydání: 2020
Předmět:
Zdroj: Magnetic resonance in medicineREFERENCES. 85(4)
ISSN: 1522-2594
Popis: Purpose To implement 3D magnetic resonance fingerprinting (MRF) with quadratic RF phase (qRF-MRF) for simultaneous quantification of T1 , T2 , ΔB0 , and T 2 ∗ . Methods 3D MRF data with effective undersampling factor of 3 in the slice direction were acquired with quadratic RF phase patterns for T1 , T2 , and T 2 ∗ sensitivity. Quadratic RF phase encodes the off-resonance by modulating the on-resonance frequency linearly in time. Transition to 3D brings practical limitations for reconstruction and dictionary matching because of increased data and dictionary sizes. Randomized singular value decomposition (rSVD)-based compression in time and reduction in dictionary size with a quadratic interpolation method are combined to be able to process prohibitively large data sets in feasible reconstruction and matching times. Results Accuracy of 3D qRF-MRF maps in various resolutions and orientations are compared to 3D fast imaging with steady-state precession (FISP) for T1 and T2 contrast and to 2D qRF-MRF for T 2 ∗ contrast and ΔB0 . The precision of 3D qRF-MRF was 1.5-2 times higher than routine clinical scans. 3D qRF-MRF ΔB0 maps were further processed to highlight the susceptibility contrast. Conclusion Natively co-registered 3D whole brain T1 , T2 , T 2 ∗ , ΔB0 , and QSM maps can be acquired in as short as 5 min with 3D qRF-MRF.
Databáze: OpenAIRE