Behavioral and electrophysiological effects of androstadienone, a human pheromone
Autor: | Bernard I. Grosser, David L. Berliner, Jennings-White Clive L, Louis Monti-Bloch |
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Rok vydání: | 2000 |
Předmět: |
Adult
medicine.medical_specialty Vomeronasal organ Endocrinology Diabetes and Metabolism Biology Pheromones Body Temperature Electrocardiography chemistry.chemical_compound Parasympathetic nervous system Endocrinology Double-Blind Method Heart Rate Parasympathetic Nervous System Reference Values Internal medicine medicine Humans Biological Psychiatry Cerebral Cortex Analysis of Variance Behavior Psychological Tests Endocrine and Autonomic Systems Respiration Androstadienone Electroencephalography Galvanic Skin Response Middle Aged Androstadienes Affect Psychiatry and Mental health Autonomic nervous system Electrophysiology Instillation Drug medicine.anatomical_structure chemistry Sex pheromone Pheromone Female Analysis of variance Vomeronasal Organ |
Zdroj: | Psychoneuroendocrinology. 25:289-299 |
ISSN: | 0306-4530 |
DOI: | 10.1016/s0306-4530(99)00056-6 |
Popis: | Androstadienone is the most prominent androstene present on male human axillary hair and on the male axillary skin surface. We have previously shown that this volatile steroid is able to stimulate [corrected] the human female vomeronasal organ in picogram (pg) quantities, resulting in changes in autonomic activity. These effects are gender-specific. The purpose of the present study was to ascertain whether androstadienone could be considered a human pheromone by altering behavior as well as autonomic function. Forty normal female subjects were randomized in a double-blind manner to receive either control or 100 pg of androstadienone directly to the vomeronasal organ. We report that administration of this steroid under these conditions results in a significant reduction of nervousness, tension and other negative feeling states. Concordant changes were observed in autonomic physiology. |
Databáze: | OpenAIRE |
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