Prevalence of iron deficiency and red blood cell transfusions in surgical patients
Autor: | Jaap Jan Zwaginga, Michael Wilson, Rik Paulus Bernardus Tonino, Martin R. Schipperus |
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Přispěvatelé: | Surgery |
Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: |
medicine.medical_specialty
Anemia iron-deficiency anaemia Gastroenterology iron deficiency Internal medicine Prevalence medicine MANAGEMENT Humans Elective surgery ANEMIA iron parameters red blood cell transfusion Retrospective Studies anaemia patient blood management HIP Anemia Iron-Deficiency biology Red Cell business.industry Transferrin saturation perioperative management Iron Deficiencies Hematology General Medicine Iron deficiency Perioperative medicine.disease Ferritin INTRAVENOUS IRON Cohort biology.protein Erythrocyte Transfusion business REQUIREMENTS CARDIAC-SURGERY |
Zdroj: | Vox Sanguinis, 117(3), 379-385. Wiley-Blackwell Publishing Ltd Vox Sanguinis, 117(3), 379-385. Wiley Vox Sanguinis, 117(3), 379-385. WILEY |
ISSN: | 0042-9007 |
Popis: | Background and Objectives While iron deficiency (ID) is the most common cause of anaemia, little is known about the prevalence and type of ID in preoperative surgical patients. The aims of the present study were to investigate the prevalence and types of ID in a large cohort of surgical patients, and how these are related to perioperative blood use after correction for confounders such as haemoglobin level.Materials and MethodsData were retrospectively extracted from electronic case records of all patients who underwent elective surgery between September 2016 and November 2017 (n = 2711). Iron parameters, haemoglobin and details of perioperative red cell transfusions were collected.ResultsOf 2711 patients, 618 (22.8%) were iron deficient (= transferrin saturation [TSAT] < 16%) preoperatively, 173 (6.4% of the cohort) had an absolute iron deficiency (AID; TSAT < 16% and ferritin < 30 mu g/L) and 445 (16.4%) had functional/mixed ID (TSAT < 16% and ferritin >= 30 mu g/L). Corrected for Hb level, iron-deficient patients received significantly more red cell units than patients without ID (p = 0.026). AID was not associated with a significantly higher incidence of transfusions (7.5% of patients transfused; p = 0.12 after correction for Hb) than patients without ID, whereas patients with functional/mixed deficiency did receive significantly more transfusions (6.1%; p = 0.021) as compared to patients without ID (1.7%).ConclusionPreoperative ID, in particular the functional/mixed type, was associated with a higher risk of receiving perioperative red cell transfusions as compared to patients without ID. Adequately treating ID might, therefore, reduce the need for perioperative red cell transfusions. |
Databáze: | OpenAIRE |
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