Autor: |
Gideon Lack, Victor Turcanu, Abdel Douiri, Suzana Radulovic, Alick Stephens, Alexandra F. Santos, George Du Toit |
Jazyk: |
angličtina |
Předmět: |
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Zdroj: |
Clinical and Translational Allergy |
ISSN: |
2045-7022 |
DOI: |
10.1186/2045-7022-5-s3-p25 |
Popis: |
Results 44 peanut allergic children (median age 5 years) reacted to peanut on DBPCPC with clinical symptoms than ranged from oral allergy syndrome to anaphylaxis. 61% of patients reacted to 0.1g of peanut protein. The mean %CD63+ basophil at 10 and 100 ng/ml of PE was independently associated with severity (p=0.012) whilst CD-sens (1/EC50x100) was independently associated with threshold (p=0.039) of allergic reactions to peanut. Severity and threshold parameters were correlated both at the clinical (Rs=-0.38; p=0.013) and at the basophil level (Rs=0.65; p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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