Retrograde Autologous Priming Method Reduces Plasma Free Hemoglobin Level in Aortic Surgery

Autor:	Aslı Demir, Uğur Aksu, Gülsüm Karduz, Aslıhan Aykut, Kübra Vardar, Eda Balcı
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Aortic arch Adult Hemodynamics law.invention Blood Transfusion Autologous Hemoglobins Axillary artery law Blood product Anesthesiology medicine.artery medicine Cardiopulmonary bypass Diseases of the circulatory (Cardiovascular) system Humans RD78.3-87.3 Cerebral perfusion pressure Aorta Hemodilution Cardiopulmonary Bypass business.industry restrictive fluid management plasma free hemoglobin General Medicine Aortic surgery Anesthesiology and Pain Medicine Treatment Outcome Anesthesia RC666-701 Original Article Cardiology and Cardiovascular Medicine business retrograde autologus priming
Zdroj:	Annals of Cardiac Anaesthesia Annals of Cardiac Anaesthesia, Vol 24, Iss 4, Pp 427-433 (2021)
ISSN:	0974-5181 0971-9784
Popis:	Background: Although conventional cardiopulmonary bypass (cCPB) is still the most widely used method in open heart surgery, methods such as retrograde autologous priming (RAP) are increasingly popular in terms of limiting hemodilution. Our hypothesis is that the use of the RAP method in aortic surgery may result in a limitation of hemodilution and a decrease in fHb levels. For this purpose, plasma free hemoglobin (fHb) levels were investigated in adult open aortic arch repair with axillary artery cannulation patients using cCPB and rRAP methods. Materials and Methods: In this study, a total of 36 patients undergoing aortic surgery using rRAP and standard cCPB were investigated. Measurements were performed at five time points: After induction of anesthesia, 5th minute of CPB, 10th minute of antegrade cerebral perfusion, 30th minute after declamping of aorta, and at sternum closure. Besides hemodynamic variables, arterial blood gas analysis and postoperative variables, patients were assessed for fHb levels. Results: The rRAP group had a significantly lower increase in fHb levels in T3, T4, and T5 time points, when compared to the cCPB group (p = 0.002, 0.047, 0.009, respectively). There was no significant difference between the rRAP and cCPB groups in other intraoperative, and postoperative variables. Also, it was observed that rRAP did not make a difference in terms of blood and blood product transfusion. Conclusion: In this study, in patients undergoing aortic surgery, a reduction in the increase of fHb was observed with the rRAP method which is a simple procedure that does not require high cost or advanced technology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1cb17c72876525fb3728b17908e750 http://europepmc.org/articles/PMC8617393 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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