Comparison of Effectiveness of Laminaria versus Vaginal Misoprostol for Cervical Preparation Before Operative Hysteroscopy in Women of Reproductive Age: A Prospective Randomized Trial

Autor: Gonca İmir Yenicesu, Meral Cetin, Caglar Yildiz, Özlem Bozoklu Akkar, Savas Karakus, Ali Cetin
Přispěvatelé: [Karakus, Savas -- Akkar, Ozlem Bozoklu -- Yildiz, Caglar -- Yenicesu, Gonca Imir -- Cetin, Meral -- Cetin, Ali] Cumhuriyet Univ, Sch Med, Dept Obstet & Gynecol, TR-58140 Sivas, Turkey, Cetin, Ali -- 0000-0002-5767-7894
Rok vydání: 2015
Předmět:
Zdroj: Journal of minimally invasive gynecology. 23(1)
ISSN: 1553-4669
2627-2687
Popis: WOS: 000368301700009
PubMed ID: 26272687
Study Objective: To compare the effectiveness and safety of intracervical laminaria dilator versus intravaginal misoprostol administered before surgery to facilitate cervical dilation before operative hysteroscopy. Design: A prospective randomized study (Canadian Task Force classification 1). Setting: A university hospital. Patients: A total of 150 women were assigned at random to the following groups: laminaria dilation (n = 50), misoprostol dilation (n = 50), and mechanical dilation (n = 50). Interventions: Hysteroscopic surgery of intrauterine lesions. Measurements and Main Results: In this study, 150 women were assigned at random to receive cervical priming with an intracervical laminaria dilator, 200 mu g of intravaginal misoprostol, or a mechanical dilator before operative hysteroscopy. Cervical response, surgical outcome, and complications of operative hysteroscopy were assessed. Visual analog scale (VAS) pain scores were recorded in the misoprostol and laminaria dilation groups. Demographic variables of the study groups were comparable (p = .278.988). The duration of cervical pretreatment was similar with the intracervical larminaria dilator and intravaginal misoprostol (p = .803); however, intravaginal misoprostol was associated with more adverse effects (p = .031). Compared with the misoprostol dilation group, in which all patients required additional cervical dilation, notably fewer patients in the laminaria dilation group required additional cervical dilation after cervical preparation (p = .001). VAS pain scores were significantly higher in the laminaria dilation group, however (p = .001). Conclusion: Cervical priming with an intracervical laminaria dilator before operative hysteroscopy reduces the need for cervical dilation and better facilitates hysteroscopic surgery compared with intravaginal misoprostol. Oral analgesic use may be required before the use of this device. Journal of Minimally Invasive Gynecology (C) 2016 AAGL. All rights reserved.
Databáze: OpenAIRE
načítá se...