A new and convenient in-situ method of generating phenyl isocyanates from anilines using oxalyl chloride

Autor:	Richard M. Goodman, P. Grant Spoors, Lynette M. Oh
Rok vydání:	2004
Předmět:	Acylation In situ chemistry.chemical_compound Aniline Oxalyl chloride Chemistry Organic Chemistry Drug Discovery Thermal decomposition Organic chemistry General Medicine Biochemistry
Zdroj:	Tetrahedron Letters. 45:4769-4771
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.04.043
Popis:	A new and convenient method of generating phenyl isocyanates from anilines using oxalyl chloride is described. Acylation of a variety of substituted aniline hydrochlorides with oxalyl chloride affords the intermediate oxamic chlorides, which smoothly undergo thermal decomposition to the corresponding isocyanates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1ada652ac0dffd0b26076f07617471 https://doi.org/10.1016/j.tetlet.2004.04.043 Zobrazit plný text záznamu Full Text from ScienceDirect