Supplementary Figures S1-S10 from Genomic Profiling of a Large Set of Diverse Pediatric Cancers Identifies Known and Novel Mutations across Tumor Spectra

Autor: Doron Lipson, Jack F. Shern, Trevor J. Pugh, Soheil Meshinchi, John M. Maris, Katherine A. Janeway, Philip J. Stephens, Vincent A. Miller, Blair Glanville, Alexis Germain, Vinny Faso, Hilary Davies, Joana Buxhaku, Jeffrey S. Ross, Rachel L. Erlich, Laurie Gay, Siraj Ali, Daniel Spritz, Samantha Morley, James X. Sun, Garrett M. Frampton, James Suh, Shakti Ramkissoon, Jo-Anne Vergilio, Julia Elvin, Jie He, Mark Bailey, Juliann Chmielecki
Rok vydání: 2023
DOI: 10.1158/0008-5472.22414374
Popis: Long tail distribution of the top 50 altered genes in pediatric sarcoma (S1); Long tail distribution of the top 50 altered genes in pediatric extracranial embryonal tumors (S2); Long tail distribution of the top 50 altered genes in pediatric brain tumors (S3); Long tail distribution of the top 50 altered genes in pediatric heme malignancies (S4); Long tail distribution of the top 50 altered genes in pediatric carcinomas (S5); Long tail distribution of the top 50 altered genes in pediatric gonadal tumors (S6); Known fusions identified in the pediatric cohort (S7); Tileplots showing the pattern of co-occurring alterations with novel MLL3 mutations (S8); Tileplot showing the pattern of co-occurring alterations with a novel PRSS1 mutation (S9); Tileplot showing the pattern of co-occurring alterations with novel DKC1 deletions (S10).
Databáze: OpenAIRE