Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases

Autor:	Alaa Alhayek, Ahmed S. Abdelsamie, Esther Schönauer, Virgyl Camberlein, Evelyn Hutterer, Gernot Posselt, Jamil Serwanja, Constantin Blöchl, Christian G. Huber, Jörg Haupenthal, Hans Brandstetter, Silja Wessler, Anna K. H. Hirsch
Rok vydání:	2022
Předmět:	Microbial Collagenase Diphosphonates Drug Discovery Molecular Medicine Collagenases Matrix Metalloproteinase Inhibitors Clostridium histolyticum
Zdroj:	Journal of medicinal chemistry. 65(19)
ISSN:	1520-4804
Popis:	In view of the worldwide antimicrobial resistance (AMR) threat, new bacterial targets and anti-infective agents are needed. Since important roles in bacterial pathogenesis have been demonstrated for the collagenase H and G (ColH and ColG) from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c172d6c12ce42b4850093f0e86b4bcc https://pubmed.ncbi.nlm.nih.gov/36154055 Zobrazit plný text záznamu