Separating Inhibitory and Excitatory Responses of Epileptic Brain to Single-Pulse Electrical Stimulation

Autor:	Sepehr Shirani, Antonio Valentin, Gonzalo Alarcon, Farhana Kazi, Saeid Sanei
Rok vydání:	2022
Předmět:	Computer Networks and Communications General Medicine
Zdroj:	International Journal of Neural Systems. 33
ISSN:	1793-6462 0129-0657
DOI:	10.1142/s0129065723500089
Popis:	To enable an accurate recognition of neuronal excitability in an epileptic brain for modeling or localization of epileptic zone, here the brain response to single-pulse electrical stimulation (SPES) has been decomposed into its constituent components using adaptive singular spectrum analysis (SSA). Given the response at neuronal level, these components are expected to be the inhibitory and excitatory components. The prime objective is to thoroughly investigate the nature of delayed responses (elicited between 100[Formula: see text]ms–1 s after SPES) for localization of the epileptic zone. SSA is a powerful subspace signal analysis method for separation of single channel signals into their constituent uncorrelated components. The consistency in the results for both early and delayed brain responses verifies the usability of the approach.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c161141907359e50635d7e9763bbedf https://doi.org/10.1142/s0129065723500089 Zobrazit plný text záznamu